Hunger and starvation in sub-Saharan Africa have lasted too long. But Africans are not consigned to a lifetime of food insecurity. The knowledge, technology and resources for closing the food security deficit are available today, and breakthroughs will continue to emerge from research and development. But no one believes it is possible simply to distribute better seeds and more fertilizer to African farmers and then to walk away. Nor will economic growth alone solve the problem. The failures that add up to food insecurity are pervasive, from agricultural, health, education and nutrition policies to research, extension services, sanitation, local government, commerce and transport. An effective response to a challenge this broad cannot be narrowed to a single intervention, discipline or institutional mandate. It will take a coordinated response across sectors.